Abstract—Traditional health information systems’ scarce security and interoperability increase the industry’s vulnerability to privacy concerns and data breaches. The distributed and transparent nature of Blockchain technology offers a solution, thereby tackling these issues. Many times, lacking robust security measures, non-compliance with regulatory standards, and fragmented data silos, conventional health information systems compromise patient privacy and trust in healthcare services. This work proposes a new architecture based on Blockchain technology to safeguard data sharing in the health sciences. Reliable data flow is ensured in the framework for safe, verifiable digital signatures by means of the Elliptic Curve Digital Signature Algorithm (ECDSA). To allow cross-chain interoperability, it mixes atomic swaps with Hash Time-Locked Contracts (HTLCs). While HTLCs ensure that transactions be carried out either within a specified period or are reversed, hence lowering fraud issues, atomic swaps allow direct transactions between several blockchains without middlemen. The entire model is conducted in a hospital setting; the proposed framework obviously increases data security and efficiency. Compared to traditional systems, using ECDSA, atomic swaps, and HTLCs reduced unauthorized access attempts by 95% and data transfer latency by 90%. Moreover, the framework guaranteed conformity to rules including HIPAA, thereby preserving patient privacy. Evaluation of the proposed technique shows its efficiency with average encryption and decryption times of 0.38 s and 0.33 s, respectively. High Peak Signal-to-Noise Ratio (PSNR) (37.5 dB) and low Mean Squared Error (MSE) (0.026) show higher preservation of image quality.
 
Keywords—blockchain, interoperability, Elliptic Curve Digital Signature Algorithm (ECDSA), Hash Time-Locked Contracts (HTLCs)


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